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To detect and characterize BAT, chemical-shift encoding-based water–fat imaging techniques have been used on the supraclavicular adipose tissue in humans across all ages, fat burner night shred. Studies in infants (48, 84, 85), children (79), adolescents (86), and adults (81, 87–94) have demonstrated the feasibility of this technique in humans. A favored method to measure BAT fat fraction is the measurement of the PDFF, which has been used in several studies for human BAT on grounds of its robustness and standardization (81, 88, 92, 94). Histological verification of MRI results was only performed in small post-mortem studies (48, 84) and in a single case of a living human adult (95). BAT Water–Fat Composition in Humans: Studies During Cold Exposure.
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